Maize Thymidine Kinase Activity Is Present throughout Plant Development and Its Heterologous Expression Confers Tolerance to an Organellar DNA-Damaging Agent
Thymidine kinase 1 (TK1) phosphorylates thymidine nucleosides to generate thymidine monophosphate.This reaction belongs to the pyrimidine salvage route that is phylogenetically conserved.In the model plant Arabidopsis thaliana, TK activity contributes to maintain nuclear and organellar genome integrity by providing deoxythymidine-triphosphate (dTTP